Organocatalysed synthesis of isoxazolines initiated by a chemoselective oxa-Michael reaction of N-BocNHOH.
نویسندگان
چکیده
An organocatalysed and chemoselective one-pot oxa-Michael-cyclocondensation reaction of N-BocNHOH to unsaturated α-ketoesters is reported which affords an original entry to enantioenriched 3-isoxazoline carboxylate derivatives as biorelevant heterocyclic frameworks.
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ورودعنوان ژورنال:
- Organic & biomolecular chemistry
دوره 12 8 شماره
صفحات -
تاریخ انتشار 2014